Testing Limits began to take shape in 2005, when Insulindependence (iD) began planning its inaugural teen expedition to Peru. At that time, iD was focused exlusively on team adventure trips. Participants came to learn more about diabetes management, but there was no formal curriculum; the responsibility of the learning was placed on the learners themselves.

Part of iD's first mission statement read as follows: "Insulindependece recognizes the dismal lack of leadership for people with diabetes, particularly in the areas of fitness and recreation. Where health institutions have failed to keep up with the rampant growth of diabetes, we aim to provide a community talent pool for the sharing of old and development of new diabetes management strategies."